GORASP1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Golgi reassembly-stacking protein 1 is a protein that in humans is encoded by the GORASP1 gene.[1]
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a membrane protein involved in establishing the stacked structure of the Golgi apparatus. It is a caspase-3 substrate, and cleavage of this encoded protein contributes to Golgi fragmentation in apoptosis. This encoded protein can form a complex with the Golgi matrix protein GOLGA2, and this complex binds to the vesicle docking protein p115. Several alternatively spliced transcript variants of this gene have been identified, but their full-length natures have not been determined.[1]
Interactions
GORASP1 has been shown to interact with TGF alpha,[2] TMED2[2] and GOLGA2.[2][3][4][5]
References
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Further reading
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