IgSF CAM

Immunoglobulin superfamily CAMs (IgSF CAMs) are a class of cell adhesion molecules.

They are either homophilic or heterophilic and bind integrins or different IgSF CAMs.

Examples

Here is a list of some molecules of this family:

• SynCAMs Synaptic Cell Adhesion Molecules
• NCAMs Neural Cell Adhesion Molecules
• ICAM-1 Intercellular Cell Adhesion Molecule
• VCAM-1 Vascular Cell Adhesion Molecule
• PECAM-1 Platelet-endothelial Cell Adhesion Molecule
• L1 family including L1 (protein), CHL1, Neurofascin and NrCAM
• SIGLEC family including Myelin-associated glycoprotein (MAG, SIGLEC-4), CD22 and CD83
• CTX family including CTX, Junctional adhesion molecule (JAM), BT-IgSF, Coxsackie virus and adenovirus receptor (CAR), VSIG, ESAM
• Nectins and nectin-like molecules
• CD2
• CD48
• Receptor tyrosine phosphatase subfamilies, including PTPRM or PTPµ subfamily members, and PTPRF or LAR subfamily members.