Murid herpesvirus 4

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Murid herpesvirus 4
Virus classification
Group:
Group I (dsDNA)
Family:
Herpesviridae
Subfamily:
Gammaherpesvirinae
Genus:
Rhadinovirus
Species:
Murid herpesvirus 4 (MuHV 4)

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Murid herpesvirus 4 (MuHV 4) is a virus in the genus Rhadinovirus. It is a member of the subfamily Gammaherpesvirinae in the family Herpesviridae. MuHV 4 infects mice via the nasal passages and causes an acute infectious mononucleosis-like syndrome with elevated levels of leukocytes, and shifts in the relative proportion of lymphocytes along with the appearance of atypical mononuclear cells.[1] Murid herpesvirus 4 currently serves as a model for study of human gamma-herpesvirus pathogenesis.[2]

Seven strains of MuHV 4 have been isolated, including the following six:

  • MHV-Šum
  • MHV-60
  • MHV-68
  • MHV-72
  • MHV-76
  • MHV-4556

References

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  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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