OSR2 (gene)

Odd-skipped related transciption factor 2
Identifiers
Symbols	OSR2 ; FLJ90037
External IDs	OMIM: 611297 MGI: 1930813 HomoloGene: 14200 GeneCards: OSR2 Gene
Gene ontology Molecular function • RNA polymerase II regulatory region sequence-specific DNA binding • transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding • protein binding • sequence-specific DNA binding • metal ion binding Cellular component • nucleus Biological process • negative regulation of transcription from RNA polymerase II promoter • metanephros development • mesonephros development • chondrocyte differentiation • transcription from RNA polymerase II promoter • positive regulation of cell proliferation • embryo development • positive regulation of gene expression • cell differentiation • positive regulation of bone mineralization • osteoblast proliferation • embryonic forelimb morphogenesis • embryonic hindlimb morphogenesis • embryonic skeletal limb joint morphogenesis • middle ear morphogenesis • odontogenesis • embryonic digit morphogenesis • positive regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • embryonic skeletal system morphogenesis • pronephros development • positive regulation of epithelial cell proliferation • palate development • embryonic skeletal joint morphogenesis • head development • bone morphogenesis • eyelid development in camera-type eye • embryonic skeletal joint development • positive regulation of gastrulation Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE OSR2 213568 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	116039	107587
Ensembl	ENSG00000164920	ENSMUSG00000022330
UniProt	Q8N2R0	Q91ZD1
RefSeq (mRNA)	NM_001142462	NM_054049
RefSeq (protein)	NP_001135934	NP_473390
Location (UCSC)	Chr 8: 98.94 – 98.95 Mb	Chr 15: 35.3 – 35.3 Mb
PubMed search	[1]	[2]

Protein odd-skipped-related 2 is a protein that in humans is encoded by the OSR2 gene. In mice, it is involved in the development of the palate and in suppressing the formation of teeth after the eruption of adult teeth.

See also

OSR1