Olfactory marker protein
| olfactory marker protein | |
|---|---|
| Identifiers | |
| Symbol | OMP |
| Entrez | 4975 |
| HUGO | 8136 |
| OMIM | 164340 |
| RefSeq | NM_006189 |
| UniProt | P47874 |
| Other data | |
| Locus | Chr. 11 q14-q21 |
| Olfactory marker protein | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| File:PDB 1jyt EBI.jpg
solution structure of olfactory marker protein from rat
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| Identifiers | |||||||||
| Symbol | Olfactory_mark | ||||||||
| Pfam | PF06554 | ||||||||
| InterPro | IPR009103 | ||||||||
| SCOP | 1jyt | ||||||||
| SUPERFAMILY | 1jyt | ||||||||
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In molecular biology, olfactory marker protein is a protein involved in signal transduction. It is a highly expressed, cytoplasmic protein found in mature olfactory sensory receptor neurons of all vertebrates. OMP is a modulator of the olfactory signal transduction cascade. The crystal structure of OMP reveals a beta sandwich consisting of eight strands in two sheets with a jelly-roll topology.[1] Three highly conserved regions have been identified as possible protein-protein interaction sites in OMP, indicating a possible role for OMP in modulating such interactions, thereby acting as a molecular switch.[2]
External links
- Olfactory marker protein at the US National Library of Medicine Medical Subject Headings (MeSH)
References
This article incorporates text from the public domain Pfam and InterPro IPR009103
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