PAK2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Serine/threonine-protein kinase PAK 2 is an enzyme that in humans is encoded by the PAK2 gene.[1][2]
Function
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.[3]
Interactions
PAK2 has been shown to interact with:
References
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Further reading
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External links
- PAK2 Info with links in the Cell Migration Gateway
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PDB gallery
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This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it. |
