PCDH18

Protocadherin 18
Identifiers
Symbols	PCDH18 ; PCDH68L
External IDs	OMIM: 608287 MGI: 1920423 HomoloGene: 10389 GeneCards: PCDH18 Gene
Gene ontology Molecular function • calcium ion binding Cellular component • plasma membrane • integral component of membrane Biological process • homophilic cell adhesion via plasma membrane adhesion molecules • brain development Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE PCDH18 gnf1h00321 at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54510	73173
Ensembl	ENSG00000189184	ENSMUSG00000037892
UniProt	Q9HCL0	Q8VHR0
RefSeq (mRNA)	NM_001300828	NM_130448
RefSeq (protein)	NP_001287757	NP_569715
Location (UCSC)	Chr 4: 137.52 – 137.53 Mb	Chr 3: 49.74 – 49.76 Mb
PubMed search	[1]	[2]

Protocadherin-18 is a protein that in humans is encoded by the PCDH18 gene.

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. This gene encodes a protein which contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Although its specific function is undetermined, the cadherin-related neuronal receptor is thought to play a role in the establishment and function of specific cell-cell connections in the brain.