PCLKC

Cadherin-related family member 2
Identifiers
Symbols	CDHR2 ; PCDH24; PCLKC
External IDs	MGI: 2687323 HomoloGene: 134510 GeneCards: CDHR2 Gene
Gene ontology Molecular function • calcium ion binding • protein binding Cellular component • brush border • integral component of membrane • apical plasma membrane • cell junction • extracellular exosome Biological process • cell adhesion • homophilic cell adhesion via plasma membrane adhesion molecules • negative regulation of cell growth Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE PCLKC 220186 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54825	268663
Ensembl	ENSG00000074276	ENSMUSG00000034918
UniProt	Q9BYE9	B9EJ32
RefSeq (mRNA)	NM_001171976	NM_001033364
RefSeq (protein)	NP_001165447	NP_001028536
Location (UCSC)	Chr 5: 176.54 – 176.6 Mb	Chr 13: 54.7 – 54.74 Mb
PubMed search	[1]	[2]

Protocadherin-24 is a protein that in humans is encoded by the PCDH24 gene.

This gene is a member of the protocadherin family, which represents a subset of the larger cadherin superfamily. The members of the protocadherin family encode non-classical cadherins that function as calcium-dependent cell-cell adhesion molecules. The kidney-expressed gene product has a signal peptide, nine cadherin repeat domains and a unique cytoplasmic region. This protocadherin represents a new candidate for tumor suppression.

Interactions

PCLKC has been shown to interact with MAST2.