Palmatine
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
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Other names
Berbericinine
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Identifiers | |
3486-67-7 | |
ChEMBL | ChEMBL274189 |
ChemSpider | 5224 |
Jmol 3D model | Interactive image |
PubChem | 19009 |
UNII | G50C034217 |
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Properties | |
C21H22NO4+ | |
Molar mass | 352.4083 g/mol |
Density | 1.23 g/cm3 |
Boiling point | 482.9 °C (901.2 °F; 756.0 K) at 760 mmHg |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Palmatine is a protoberberine alkaloid found in several plants including Phellodendron amurense, Rhizoma coptidis/Coptis Chinensis and Corydalis yanhusuo.[1]
It is the major component of the protoberberine extract from Enantia chlorantha.[2]
It has been studied for its potential use in the treatment of jaundice, dysentery, hypertension, inflammation, and liver-related diseases.[3] This compound also has weak in vitro activity against flavivirus.[4]
See also
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Virtanen P., Njimi T.,Ekotto Mengata D.:Clinical trials of hepatitis cure with protoberberine alkaloids of Enantia Chlorantha (abstract) Eur.J.Clin.Pharmacol.36: A123, 1989b
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Jia F., Zou G., Fan J., Yuan Z."Identification of palmatine as an inhibitor of West Nile virus" Archives of Virology 2010 155:8 (1325-1329)
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- Chemical articles using a fixed chemical formula
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- Alkaloids
- Quaternary ammonium compounds
- Phenol ethers
- Isoquinolinoisoquinolines
- Organic compound stubs