Quinfamide

Quinfamide

170px
Systematic (IUPAC) name
[1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
Clinical data
Routes of administration	Oral
Identifiers
CAS Number	62265-68-3 N
ATC code	None
PubChem	CID: 71743
ChemSpider	64787 N
UNII	O1ZB1046R1 Y
Chemical data
Formula	C16H13Cl2NO4
Molecular mass	354.18472 g/mol
SMILES C1CC2=C(C=CC(=C2)OC(=O)C3=CC=CO3)N(C1)C(=O)C(Cl)Cl
InChI InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2 N Key:SBJGFIXQRZOVTO-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Quinfamide, is a drug that has anti-parasitic properties.

Synthesis

Quinfamide is one of a relatively small family of antiamoebic compounds containing a dichloroacetamide function.

File:Quinfamide synthesis.svg

Quinfamide synthesis:

The synthesis begins by amidation of 6-hydroxytetrahydroquinoline with dichloroacetyl chloride. The sequence is completed by acylation with 2-furoyl chloride.