RU28362
From Infogalactic: the planetary knowledge core
Molecular structure of RU28362 | |
Names | |
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IUPAC name
(11β,17β)-11,17-Dihydroxy-6-methyl-17-(1-propynyl)-androsta-1,4,6-trien-3-one
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Identifiers | |
74915-64-3 | |
ChemSpider | 110341 |
3445 | |
Jmol 3D model | Interactive image |
PubChem | 123790 |
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Properties | |
C23H28O3 | |
Molar mass | 352.47 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
RU28362 is a synthetic molecule in the steroid family developed by the Roussel Uclaf pharmaceutical company, after which it was named. RU28362 or RU-28362 is a specific receptor agonist, i.e. binds the glucocorticoid receptor (Corticoid Type II Receptor) but not the mineralocorticoid receptor (Corticoid Type I Receptor).[1][2]
A similar compound is dexamethasone that also specifically binds the Type II receptor with high affinity. This is in contrast to the natural steroid hormones cortisol or corticosterone, which bind both receptors, though they bind to Type I with greater affinity.[3]
References
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