Raja M. Flores

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Raja Michael Flores, M.D.
Education Columbia University
New York University
Albert Einstein College of Medicine
Medical career
Profession thoracic surgeon
Institutions Mount Sinai Hospital
Research cancer research

Raja Michael Flores, M.D., is an American thoracic surgeon, currently Chief of the Division of Thoracic Surgery at Mount Sinai Hospital and Ames Professor of Cardiothoracic Surgery at the Icahn School of Medicine at Mount Sinai, both in New York City.[1]

Biography

Flores received a B.A. in biochemistry from New York University in 1988 and his M.D. from Albert Einstein College of Medicine in 1992. His internship (1992–1993) and residency (1993–1997) at Columbia-Presbyterian Medial Center were followed by a Thoracic Oncology Clinical Research Fellowship (1997–1998) in Intraoperative Chemotherapy, Mesothelioma and Lung Cancer at Brigham and Women's Hospital/Dana-Farber Cancer Institute, and a Cardiothoracic Surgery Residency (1998-2000) at Harvard Medical School, both in Boston, Massachusetts.[2][3]

Flores is currently an editorial board member for the World Journal of Gastrointestinal Surgery, the World Journal of Gastrointestinal Edoscopy and the World Journal of Respirology. He is a reviewer for 13 other journals including Head & Neck, the Journal of Thoracic and Cardiovascular Surgery, the Journal of Thoracic Oncology and the Journal of Clinical Oncology. Memberships include the American College of Chest Physicians, the American College of Surgeons Oncology Group and the American Society of Clinical Oncology.[4]

Research

Flores' research has significantly impacted the surgical management of pleural mesothelioma by demonstrating that partial pleural membrane removal is as effective a treatment as lung removal.[5] He was instrumental in creating VATS lobectomy as the standard in the surgical treatment of lung cancer[6][7][8] and is considered a pioneer in the use of intraoperative chemotherapy for mesothelioma.[9]

Flores is the author of more than 60 book chapters, reviews, monographs and abstracts and more than 150 publications. He serves as a reviewer for 13 journals and has been an editorial board member on four journals. He is the principal investigator on five clinical trials and has been ranked in the top 1% in his field by U.S. News & World Report.[5][10]

Flores areas of interest include lung cancer screening, thoracoscopy, VATS lobectomy, extrapleural pneumonectomy for mesothelioma, asbestos, tracheal stenosis, carinal surgery and esophageal cancer surgery.[11] He is the principal investigator for a clinical trial of neoadjuvant gemcitabine and cisplatin followed by extrapleural pneumonectomy and high-dose radiation.[4]

Other research includes:

Role Title Affiliation
Co-Principal Investigator Extrapleural Pneumonectomy Followed by Intrathoracic/Intraperitoneal Heated Cisplatin and Intravenous Sodium Thiosulfate in the Multimodality Treatment of Malignant Pleural Mesothelioma: A Phase I Study Brigham & Women's Hospital
Principal Investigator Randomized, Prospective Trial of Mediastinal LN Sampling Vs. Complete Lymphadenectomy During Conduct of Pulmonary Resection in Patients with N0 and N1 (less than hilar) non-small cell carcinoma (ACOSOG Z0030) Memorial Sloan-Kettering Cancer Center
Principal Investigator A Randomized Phase III Trial Surgery Alone or Surgery Plus Preoperative

Paclitaxel/Carboplatin in Clinical Stage IB (T2N0), II (T1-2N1, T3N0) and selected IIIA None Small Cell Lung Cancer (NSCLC) – (RTOGL-0015 (S9900)

Memorial Sloan-Kettering Cancer Center
Principal Investigator The Role of Laparoscopic Staging in Patients with Resectable Gastroesophageal Junction Carcinomas Memorial Sloan-Kettering Cancer Center
Principal Investigator A Phase II Trial of Induction Chemotherapy, Surgical Resection and Adjuvant External Beam Radiation for Locally Advanced Malignant Pleural Mesothelioma Memorial Sloan-Kettering Cancer Center
Principal Investigator A Phase II Trial of Induction Chemotherapy, Surgical Resection, and Adjuvant External Beam Radiation for Locally Advanced Malignant Pleural Mesothelioma Lilly Research Laboratories

Publications

Partial list:

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  • Flores RM, Pass HI, Seshan VE, Dycoco J, Zakowski M, Carbone M, Bains MS, Rusch VW. "Extrapleural Pneumonectomy (EPP) versus Pleurectomy/Decortication (P/D) in the surgical management of malignant pleural mesothelioma (MPM): Results in 663 patients. J Thorac Cardiovasc Surg 2008 Mar; 135(3):620-6, 626.el-3. doi:10.1016/j.jtcvs.2007.10.054 PMID 18329481
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  • Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM Jr, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ. "Resection margins, extrapleural nodal status, and cell type determine survival in trimodality therapy of malignant pleural mesothelioma (MPM): Results in 183 patients. Seventy-eighth meeting of the American Association of Thoracic Surgery. 1998. Boston, MA. PMID 9869758

References

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External links