Resiquimod

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Resiquimod
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Systematic (IUPAC) name
1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
Clinical data
Legal status
  • Investigational
Routes of
administration
Topical
Identifiers
CAS Number 144875-48-9 YesY
ATC code none
PubChem CID: 159603
IUPHAR/BPS 5051
ChemSpider 140330 N
UNII V3DMU7PVXF N
ChEMBL CHEMBL383322 N
Chemical data
Formula C17H22N4O2
Molecular mass 314.382 g/mol
  • CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
  • InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19) N
  • Key:BXNMTOQRYBFHNZ-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Resiquimod (R-848) is a drug that acts as an immune response modifier, and has antiviral and antitumour activity. It is used as a topical gel[1] in the treatment of skin lesions[2] such as those caused by the herpes simplex virus[3][4] and cutaneous T cell lymphoma,[5] and as an adjuvant to increase the effectiveness of vaccines.[6] It has several mechanisms of action, being both an agonist for toll-like receptor 7 and 8,[7] and an upregulator of the opioid growth factor receptor.[8]

See also

References

  1. Patents #5, 939, 090 and 6, 365, 166
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