S100A11

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S100 calcium-binding protein A11 (S100A11) is a protein that in humans is encoded by the S100A11 gene.[1][2]

Function

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis.[2]

Interactions

S100A11 has been shown to interact with Nucleolin[3] and S100B.[4]

References

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Further reading

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