SAT2

This article is about the human gene. For the submarine communications cable, see SAT-2. For the SAT II tests, see SAT Subject Tests.

Spermidine/spermine N1-acetyltransferase family member 2
250px PDB rendering based on 2bei.
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 2BEI, 2Q4V
Identifiers
Symbols	SAT2 ; SSAT2
External IDs	OMIM: 611463 MGI: 1916465 HomoloGene: 44215 GeneCards: SAT2 Gene
EC number	2.3.1.57
Gene ontology Molecular function • diamine N-acetyltransferase activity Cellular component • cytoplasm • extracellular exosome Biological process • putrescine catabolic process • spermidine acetylation • spermine acetylation • putrescine acetylation • nor-spermidine metabolic process Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	112483	69215
Ensembl	ENSG00000141504	ENSMUSG00000069835
UniProt	Q96F10	Q6P8J2
RefSeq (mRNA)	NM_133491	NM_026991
RefSeq (protein)	NP_597998	NP_081267
Location (UCSC)	Chr 17: 7.63 – 7.63 Mb	Chr 11: 69.62 – 69.62 Mb
PubMed search	[1]	[2]

Diamine acetyltransferase 2 is an enzyme that in humans is encoded by the SAT2 gene. SAT2 maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate.