Template:PBB/1437

Colony stimulating factor 2 (granulocyte-macrophage)
PDB rendering based on 2gmf
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1CSG, 2GMF, 3CXE
Identifiers
Symbols	CSF2 ; GMCSF
External IDs	OMIM: 138960 MGI: 1339752 HomoloGene: 600 GeneCards: CSF2 Gene
Gene ontology Molecular function • cytokine activity • granulocyte macrophage colony-stimulating factor receptor binding • protein binding • growth factor activity Cellular component • extracellular region • extracellular space Biological process • embryonic placenta development • immune response • positive regulation of cell proliferation • positive regulation of gene expression • positive regulation of macrophage derived foam cell differentiation • positive regulation of interleukin-23 production • epithelial fluid transport • macrophage activation • positive regulation of tyrosine phosphorylation of Stat5 protein • myeloid dendritic cell differentiation • positive regulation of DNA replication • negative regulation of cytolysis • cellular response to lipopolysaccharide • positive regulation of podosome assembly • dendritic cell differentiation • negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1437	12981
Ensembl	ENSG00000164400	ENSMUSG00000018916
UniProt	P04141	P01587
RefSeq (mRNA)	NM_000758	NM_009969
RefSeq (protein)	NP_000749	NP_034099
Location (UCSC)	Chr 5: 132.07 – 132.08 Mb	Chr 11: 54.25 – 54.25 Mb
PubMed search	[1]	[2]