Template:PBB/2056

Erythropoietin
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1BUY, 1CN4, 1EER
Identifiers
Symbols	EPO ; EP; MVCD2
External IDs	OMIM: 133170 MGI: 95407 HomoloGene: 624 ChEMBL: 5837 GeneCards: EPO Gene
Gene ontology Molecular function • erythropoietin receptor binding • hormone activity • protein binding • protein kinase activator activity Cellular component • extracellular region • extracellular space • cell surface Biological process • apoptotic process • signal transduction • embryo implantation • aging • blood circulation • positive regulation of cell proliferation • response to salt stress • negative regulation of calcium ion transport into cytosol • peptidyl-serine phosphorylation • activation of protein kinase activity • response to lipopolysaccharide • response to vitamin A • response to testosterone • positive regulation of tyrosine phosphorylation of Stat5 protein • hemoglobin biosynthetic process • erythrocyte maturation • response to estrogen • positive regulation of neuron differentiation • positive regulation of DNA replication • positive regulation of transcription, DNA-templated • positive regulation of Ras protein signal transduction • response to axon injury • response to electrical stimulus • response to hyperoxia • regulation of transcription from RNA polymerase II promoter in response to hypoxia • response to interleukin-1 • cellular response to hypoxia • cellular hyperosmotic response • negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress • negative regulation of erythrocyte apoptotic process • negative regulation of cation channel activity Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2056	13856
Ensembl	ENSG00000130427	ENSMUSG00000029711
UniProt	P01588	P07321
RefSeq (mRNA)	NM_000799	NM_007942
RefSeq (protein)	NP_000790	NP_031968
Location (UCSC)	Chr 7: 100.72 – 100.72 Mb	Chr 5: 137.48 – 137.53 Mb
PubMed search	[1]	[2]