Template:PBB/54205

Cytochrome c, somatic
Three-dimensional structure of cytochrome c (green) with a heme molecule coordinating a central Iron atom (orange).
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 1J3S, 3NWV, 3ZCF, 3ZOO
Identifiers
Symbols	CYCS ; CYC; HCS; THC4
External IDs	OMIM: 123970 MGI: 88578 HomoloGene: 133055 GeneCards: CYCS Gene
Gene ontology Molecular function • protein serine/threonine phosphatase activity • protein binding • heme binding • electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity • metal ion binding Cellular component • protein phosphatase type 2A complex • nucleus • mitochondrion • mitochondrial inner membrane • mitochondrial intermembrane space • cytosol • respiratory chain Biological process • response to reactive oxygen species • mitochondrial electron transport, ubiquinol to cytochrome c • mitochondrial electron transport, cytochrome c to oxygen • apoptotic DNA fragmentation • transcription initiation from RNA polymerase II promoter • apoptotic process • organelle organization • mitochondrion organization • activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c • gene expression • programmed cell death • dephosphorylation • respiratory electron transport chain • ATP synthesis coupled electron transport • cellular metabolic process • small molecule metabolic process • cellular respiration • intrinsic apoptotic signaling pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	54205	13063
Ensembl	ENSG00000172115	ENSMUSG00000063694
UniProt	P99999	P62897
RefSeq (mRNA)	NM_018947	NM_007808
RefSeq (protein)	NP_061820	NP_031834
Location (UCSC)	Chr 7: 25.12 – 25.13 Mb	Chr 6: 50.56 – 50.57 Mb
PubMed search	[1]	[2]