Girentuximab
From Infogalactic: the planetary knowledge core
Monoclonal antibody | |
---|---|
Type | Whole antibody |
Source | Chimeric |
Target | CA-IX |
Clinical data | |
Trade names | Rencarex |
Identifiers | |
CAS Number | 916138-87-9 |
ATC code | none |
UNII | 539B57DFJF |
Chemical data | |
Formula | C6460H10006N1718O2018S48 |
Molecular mass | 146.5 kg/mol |
(what is this?) (verify) |
Girentuximab (trade name Rencarex) is a chimeric monoclonal antibody to carbonic anhydrase IX.[1] It is investigational agent in clinical trials for renal cell carcinoma.[2]
Girentuximab was developed by Wilex AG.
It triggers antibody-dependent cell-mediated cytotoxicity (ADCC). It does this by activating natural killer cells by binding to carbonic anhydrase IX.[3]
References
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- ↑ Girentuximab (Rencarex) for renal cell carcinoma
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Categories:
- Chemical articles having calculated molecular weight overwritten
- Drugs that are a monoclonal antibody
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