SB-408124
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Systematic (IUPAC) name | |
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1-(6,8-difluoro-2-methylquinolin-4-yl)-3-[4-(dimethylamino)phenyl]urea
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Identifiers | |
CAS Number | 288150-92-5 |
PubChem | CID: 4331799 |
IUPHAR/BPS | 1704 |
ChemSpider | 3536200 |
Chemical data | |
Formula | C19H18F2N4O |
Molecular mass | 356.368 g/mol |
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SB-408124 is a drug which is a non-peptide antagonist selective for the orexin receptor subtype OX1, with around 70x selectivity for OX1 over OX2 receptors, and improved oral bioavailability compared to the older OX1 antagonist SB-334867. It is used in scientific research into the function of orexinergic neurons in the body.[1][2]
References
- REDIRECT Template:Peptide receptor modulators
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Categories:
- Chemical articles having calculated molecular weight overwritten
- Articles with changed InChI identifier
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- Drugs with no legal status
- Orexin antagonists
- Organofluorides
- Quinolines
- Sedatives
- Ureas
- Sedative stubs