TSPAN3

Tetraspanin 3
Identifiers
Symbols	TSPAN3 ; TM4-A; TM4SF8; TSPAN-3
External IDs	OMIM: 613134 MGI: 1928098 HomoloGene: 21168 GeneCards: TSPAN3 Gene
Gene ontology Molecular function • molecular_function Cellular component • integral component of membrane • extracellular exosome Biological process • biological_process Sources: Amigo / QuickGO
RNA expression pattern
File:PBB GE TSPAN3 200972 at tn.png
File:PBB GE TSPAN3 200973 s at tn.png
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	10099	56434
Ensembl	ENSG00000140391	ENSMUSG00000032324
UniProt	O60637	Q9QY33
RefSeq (mRNA)	NM_001168412	NM_019793
RefSeq (protein)	NP_001161884	NP_062767
Location (UCSC)	Chr 15: 77.04 – 77.08 Mb	Chr 9: 56.14 – 56.16 Mb
PubMed search	[1]	[2]

Tetraspanin-3 is a protein that in humans is encoded by the TSPAN3 gene.

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.

External links

• TSPAN3 human gene location in the UCSC Genome Browser.
• TSPAN3 human gene details in the UCSC Genome Browser.