Tromantadine
From Infogalactic: the planetary knowledge core
Skeletal formula | |
Ball-and-stick model | |
Systematic (IUPAC) name | |
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N-1-adamantyl-N-[2-(dimethylamino)ethoxy]acetamide
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Clinical data | |
AHFS/Drugs.com | International Drug Names |
Routes of administration |
Topical |
Identifiers | |
CAS Number | 53783-83-8 ![]() |
ATC code | D06BB02 (WHO) J05AC03 |
PubChem | CID: 64377 |
ChemSpider | 57947 ![]() |
UNII | H191JFG8WA ![]() |
KEGG | D07199 ![]() |
NIAID ChemDB | 007760 |
Chemical data | |
Formula | C16H28N2O2 |
Molecular mass | 280.406 g/mol |
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Tromantadine is an antiviral medicine used to treat herpes simplex virus. It is available in a topical gel under trade name Viru-Merz. Its performance is similar to aciclovir.
Like rimantadine, amantadine, and adapromine, tromantadine is a derivative of adamantane.
Mechanism
Tromantadine inhibits the early and late events in the virus replication cycle.[1] It changes the glycoproteins of the host cells, therefore impeding the absorption of the virus. It inhibits penetration of the virus. It also prevents uncoating of the virions.
References
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External links
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Categories:
- Pages with broken file links
- Chemical articles having calculated molecular weight overwritten
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- Drugs with no legal status
- Anti-herpes virus drugs
- Adamantanes
- Acetamides
- Amines
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