Alpha-v beta-3

α_Vβ₃ is a type of integrin that is a receptor for vitronectin.^[1] It consists of two components, integrin alpha V and integrin beta 3 (CD61), and is expressed by platelets. Furthermore, it is a receptor for phagocytosis on macrophages or dendritic cells.^[2]

Inhibitors like etaracizumab may be used as antiangiogenics.

References

integrin alphaVbeta3 at the US National Library of Medicine Medical Subject Headings (MeSH)

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v t e Antiangiogenics
Endogenous Regulation	Angiopoietin 2 angiostatin canstatin calreticulin endostatin IFN-α IFN-β IFN-γ CXCL10 IL-4 IL-12 IL-18 maspin Meth-1 Meth-2 osteopontin platelet factor-4 prolactin proliferin-related protein prothrombin (kringle domain-2) antithrombin III fragment SPARC Thrombospondin 1 TIMP vasostatin VEGI soluble VEGFR-1 NRP-1 CDAI
Exogenous Regulation	2-Methoxyestradiol α_Vβ₃ inhibitors angiostatic steroids heparin angiostatin bevacizumab carboxyamidotriazole Cartilage-Derived Angiogenesis Inhibitory Factor CM101 endostatin IFN-α IL-12 itraconazole linomide matrix metalloproteinase inhibitors platelet factor-4 prolactin SU5416 suramin tasquinimod tecogalan tetrathiomolybdate thalidomide thrombospondin thrombospondin TNP-470 VEGFR antagonists
See also	Angiogenesis Angiogenesis inhibitors