FLNB

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Filamin B, beta (FLNB), also known as Filamin B, beta (actin binding protein 278), is a cytoplasmic protein which in humans is encoded by the FLNB gene.

FLNB regulates intracellular communication and signalling by cross-linking the protein actin to allow direct communication between the cell membrane and cytoskeletal network, to control and guide proper skeletal development.[1]

Mutations in the FLNB gene are involved in several lethal bone dysplasias, including boomerang dysplasia and atelosteogenesis type I.[2][3][4]


Interactions

FLNB has been shown to interact with GP1BA,[5] Filamin,[6] FBLIM1,[7] PSEN1,[8] CD29[9] and PSEN2.[8]

See also

References

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  8. ↑ 8.0 8.1 Lua error in package.lua at line 80: module 'strict' not found.
  9. ↑ Lua error in package.lua at line 80: module 'strict' not found.

External links

Further reading

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