Small nucleolar RNA Z221
| Small nucleolar RNA Z221/R21b | |
|---|---|
| 220px | |
| Predicted secondary structure and sequence conservation of snoZ221_snoR21b | |
| Identifiers | |
| Symbol | snoZ221_snoR21b |
| Alt. Symbols | snoZ221 |
| Rfam | RF00300 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; CD-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0001263 |
Small nucleolar RNA Z221 is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifiying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
snoRNA Z221 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
Plant snoRNA Z221 was identified in a screen of Oryza sativa.[2]
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