Class C GPCR
7 transmembrane receptor (metabotropic glutamate family) | |||||||||
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Identifiers | |||||||||
Symbol | 7tm_3 | ||||||||
Pfam | PF00003 | ||||||||
InterPro | IPR000337 | ||||||||
PROSITE | PDOC00754 | ||||||||
TCDB | 9.A.14 | ||||||||
OPM superfamily | 6 | ||||||||
OPM protein | 4or2 | ||||||||
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The class C G-protein-coupled receptors (IPR000337) are a class of G-protein coupled receptors that include the metabotropic glutamate receptors (IPR000162) and several additional receptors.[1]
Structurally they are composed of four elements; an N-terminal signal sequence; a large hydrophilic extracellular agonist-binding region containing several conserved cysteine residues which could be involved in disulphide bonds; a shorter region containing seven transmembrane domains; and a C-terminal cytoplasmic domain of variable length Lua error in package.lua at line 80: module 'strict' not found.. This protein family includes metabotropic glutamate receptors, the extracellular calcium-sensing receptors, the gamma-amino-butyric acid (GABA) type B receptors, and the vomeronasal type-2 receptors
Contents
Subfamilies
- extracellular calcium-sensing receptor-related IPR000068
GABAB receptors
- GABAB receptor (gamma-aminobutyric acid) IPR002455
Metabotropic glutamate receptors
RAIG
Taste receptors
Orphan
Other
- Bride of sevenless protein IPR002956
- Vomeronasal receptor, type 2 IPR004073
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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