SLC6A15
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Solute carrier family 6 member 15 (SLC6A15) also known as the sodium-dependent neutral amino acid transporter B(0)AT2 (B0AT2)' is a protein that in humans is encoded by the SLC6A15 gene.[1]
Function
SLC6A15 shows structural characteristics of an Na+ and Cl−-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[2]
Clinical relevance
Variants of this gene linked with depression are associated with reduced SLC6A15 expression in the human hippocampus, as well as decreased volume of this brain region.[3]
References
Further reading
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