Isoconazole

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Isoconazole
Isoconazole.svg
Systematic (IUPAC) name
(RS)-1-[2-[(2,6-Dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
Clinical data
AHFS/Drugs.com International Drug Names
Identifiers
CAS Number 27523-40-6
ATC code D01AC05 (WHO) G01AF07
PubChem CID: 3760
DrugBank DB08943 N
ChemSpider 3629
UNII GRI7WFR424 YesY
KEGG D04624
ChEBI CHEBI:82865 YesY
ChEMBL CHEMBL1571863
Chemical data
Formula C18H14Cl4N2O
Molecular mass 416.127 g/mol
  • Clc1ccc(c(Cl)c1)C(OCc2c(Cl)cccc2Cl)Cn3ccnc3

Isoconazole is an azole antifungal drug and could inhibit gram positive bacteria.[1][2] Nigerian and British medical researchers found that for foot and vaginal infections, isoconazole has a similar effectiveness to clotrimazole.[3][4] Isoconazole nitrate may be used in combination with corticosteroid diflucortolone to increase its bioavailability.[1]

References

  1. ↑ 1.0 1.1 Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ The Merck Index, 12th Edition, 5176
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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