Nodular sclerosis
From Infogalactic: the planetary knowledge core
| Nodular sclerosis | |
|---|---|
| File:Hodgkin's disease, nodular sclerosis.jpg
Nodular sclerosis. The distinct nodules on the cut surface of this lymph node strongly suggest the diagnosis.
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| Classification and external resources | |
| Specialty | Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value). |
| ICD-10 | C81.1 |
| ICD-9-CM | 201.5 |
| ICD-O | M9663/3-9667/3 |
| Patient UK | Nodular sclerosis |
Nodular sclerosis (or "NSHL") is a form of Hodgkin's lymphoma[1] that is the most common subtype of HL in developed countries. It affects females slightly more than males and has a median age of onset at ~28 years. It is composed of large tumor nodules with lacunar Reed–Sternberg cell (RS cells) surrounded by fibrotic collagen bands.
The British National Lymphoma Investigation further categorized NSHL based upon Reed-Sternberg cells into "nodular sclerosis type I" (NS I) and "nodular sclerosis type II" (NS II), with the first subtype responding better to treatment. [2]
References
External links
- Illustration, at UMDNJ
- Illustration
- PubMed - use of Erythropoietin
- Subtypes
- Lymphoma Association information on nodular sclerosing
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