Porcelain gallbladder

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Porcelain gallbladder
File:Porcelain gallbladder.png
Porcelain gallbladder on X-ray
Classification and external resources
Specialty Lua error in Module:Wikidata at line 446: attempt to index field 'wikibase' (a nil value).
ICD-9-CM 575.8
eMedicine radio/569
Patient UK Porcelain gallbladder
[[[d:Lua error in Module:Wikidata at line 863: attempt to index field 'wikibase' (a nil value).|edit on Wikidata]]]

Porcelain gallbladder is a calcification of the gallbladder believed to be brought on by excessive gallstones, although the exact cause is not clear. As with gallstone disease in general, this condition occurs predominantly in overweight female patients of middle age. It is a morphological variant of chronic cholecystitis. Inflammatory scarring of the wall, combined with dystrophic calcification within the wall transforms the gallbladder into a porcelain-like vessel. Removal of the gallbladder (cholecystectomy) is the recommended treatment.

Association with cancer

Porcelain gallbladder is associated with gallbladder cancer, but the precise nature of the association is uncertain. Two review articles examined the association between cancer of the gallbladder and calcified gallbladder. One study reported an incidence of gallbladder cancer of about 1% in patients with calcified gallbladder.[citation needed] Another study found that of 69 calcified gallbladders, 3 of them contained cancer.[1][2] A recent review of 340 patients showed an overall rate of gallbladder malignancy in patients with gallbladder wall calcification of 6%.[3]

Symptoms

Symptoms can include abdominal pain (especially after eating), jaundice, and vomiting. First symptom to appear is jaundice followed by right upper quadrant pain. in the wall of the gallbladder

Diagnosis

Abdominal radiography (X-ray), abdominal ultrasound or CT scan.

Treatment

Due to the increased risk for gallbladder cancer, the recommended treatment is cholecystectomy which usually includes pre-operative or intra-operative imaging of the biliary tree. Cholecystectomy may be performed via an open incision or via laparoscopic methods, but gallbladder anatomy and consistency may complicate the operation.[4]

References

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External links

  • eMedicine.com – Porcelain Gallbladder by Ali Nawaz Khan and Margaret Aird