A-68930
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
(1R,3S)-1-(Aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol[1]
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Identifiers | |
130465-45-1 ![]() 130465-39-3 (HCl) ![]() |
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ChEMBL | ChEMBL315468 ![]() |
ChemSpider | 109076 ![]() |
6077 | |
Jmol 3D model | Interactive image |
MeSH | A+68930 |
PubChem | 122324 |
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Properties | |
C16H17NO3 | |
Molar mass | 271.32 g·mol−1 |
log P | 1.175 |
Acidity (pKa) | 9.491 |
Basicity (pKb) | 4.506 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
A-68930 is a synthetic compound that acts as a selective dopamine receptor D1 partial agonist.[2][3] It is orally active and has antidepressant and anorectic effects in animals, producing wakefulness and tachycardia,[4][5][6][7] but without stimulant effects, instead producing sedation.[8][9] The difference in effects between A-68930 and other D1 agonists such as SKF-82958 may be due to their differing effects on the related D5 receptor.[10]
References
- ↑ CID 122324 from PubChem
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Categories:
- Chemical articles with multiple CAS Registry Numbers
- Articles without KEGG source
- Articles without UNII source
- Articles with changed InChI identifier
- Pages using collapsible list with both background and text-align in titlestyle
- Dopamine agonists
- Isochromenes
- Catechols
- Nervous system drug stubs
- Organic compound stubs