EXP-561

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EXP-561
EXPfivesixone.png
Systematic (IUPAC) name
4-phenylbicyclo[2.2.2]octan-1-amine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration
Oral
Identifiers
CAS Number 10206-89-0
16142-83-9 (hydrochloride monohydrate)
ATC code none
PubChem CID: 27696
ChemSpider 25769
Chemical data
Formula C14H19N
Molecular mass 201.31 g/mol
  • NC12CCC(CC1)(CC2)C3=CC=CC=C3

EXP-561[1] is an investigational drug that acts as an inhibitor of the reuptake of serotonin, dopamine, and norepinephrine.[2][3][4][5] It was developed in the 1960s by Du Pont[6] and was suggested as a potential antidepressant but failed in trials[7] and was never marketed.[5][8][9][10]

References

  1. US 3362878 - Pharmaceutical compositions and methods utilizing substituted bicyclo[2.2.2]-octanes
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  6. US Patent 3308160 - PHENYLBICYCLO[Z.Z.Z]OCTANE-L-AMINES AND SALTS THEREOF
  7. INTERNATIONAL REVIEW NEUROBIOLOGY, Volume 12 Page 160
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