Alizapride

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Alizapride
Alizapride.svg
3D Alizapride.png
Systematic (IUPAC) name
N-[(1-Allylpyrrolidin-2-yl)methyl]-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
Clinical data
AHFS/Drugs.com International Drug Names
Legal status
  • ℞ (Prescription only)
Routes of
administration
Oral, IM, IV
Pharmacokinetic data
Biological half-life 3 hours
Excretion Renal
Identifiers
CAS Number 59338-93-1 YesY
ATC code A03FA05 (WHO)
PubChem CID: 43008
DrugBank DB01425 YesY
ChemSpider 39202 YesY
UNII P55703ZRZY YesY
KEGG D07102 YesY
ChEMBL CHEMBL290194 YesY
Chemical data
Formula C16H21N5O2
Molecular mass 315.37 g/mol
  • O=C(c2cc1nnnc1cc2OC)NCC3N(C\C=C)CCC3
  • InChI=1S/C16H21N5O2/c1-3-6-21-7-4-5-11(21)10-17-16(22)12-8-13-14(19-20-18-13)9-15(12)23-2/h3,8-9,11H,1,4-7,10H2,2H3,(H,17,22)(H,18,19,20) YesY
  • Key:KSEYRUGYKHXGFW-UHFFFAOYSA-N YesY
  (verify)

Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is structurally related to metoclopramide and other benzamides.[1]

References

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