Wee1-like protein kinase

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). WEE1 homolog (S. pombe), also known as WEE1, is a protein which in humans is encoded by the WEE1 gene.[1]

Function

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.[2]

Interactions

Wee1-like protein kinase has been shown to interact with YWHAB[3] and PIN1.[4]

References

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External links

Further reading

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