MAM-2201

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MAM-2201
MAM-2201 structure.png
Systematic (IUPAC) name
(1-(5-fluoropentyl)-1H-indol-3-yl)(4-methyl-1-naphthalenyl)-methanone
Clinical data
Legal status
Identifiers
CAS Number 1354631-24-5 YesY
PubChem CID: 66570720
ChemSpider 28289977
Chemical data
Formula C25H24FNO
Molecular mass 373.462 g/mol
  • FCCCCCn(c4)c2ccccc2c4C(=O)c3ccc(C)c1ccccc13
  • InChI=1S/C25H24FNO/c1-18-13-14-22(20-10-4-3-9-19(18)20)25(28)23-17-27(16-8-2-7-15-26)24-12-6-5-11-21(23)24/h3-6,9-14,17H,2,7-8,15-16H2,1H3
  • Key:IGBHZHCGWLHBAE-UHFFFAOYSA-N

MAM-2201 (4'-methyl-AM-2201, 5"-fluoro-JWH-122) is a drug that presumably acts as a potent agonist for the cannabinoid receptors.[1] It had never previously been reported in the scientific or patent literature, and was first identified by laboratories in the Netherlands and Germany in June 2011 as an ingredient in synthetic cannabis smoking blends.[2][3][4] Like RCS-4 and AB-001, MAM-2201 thus appears to be a novel compound invented by "research chemical" suppliers specifically for grey-market recreational use. Structurally, MAM-2201 is a hybrid of two known cannabinoid compounds JWH-122 and AM-2201, both of which had previously been used as active ingredients in synthetic cannabis blends before being banned in many countries.

A study of MAM-2201 in rats showed that it causes neurofunctional disruptions.[5]

Legal Status

MAM-2201 has been banned by being added to the temporary class drug schedule in New Zealand, effective from 13 July 2012.[6]

As of October 2015 MAM-2201 is a controlled substance in China.[7]

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ EMCDDA–Europol 2011 Annual Report on the implementation of Council Decision 2005/387/JHA
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Temporary Class Drug Notice, 5 July 2012. NZ Department of Internal Affairs.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.


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