LP-12

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LP-12
240px
Systematic (IUPAC) name
4-(2-diphenyl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)-1-piperazinehexanamide
Identifiers
PubChem CID: 23643664
ChemSpider 22439715 N
Chemical data
Formula C32H39N3O
Molecular mass 481.670 g/mol
  • C5CCc1ccccc1C5NC(=O)CCCCCN3CCN(CC3)c2ccccc2-c4ccccc4
  • InChI=1S/C32H39N3O/c36-32(33-30-18-11-15-26-14-6-7-16-28(26)30)20-5-2-10-21-34-22-24-35(25-23-34)31-19-9-8-17-29(31)27-12-3-1-4-13-27/h1,3-4,6-9,12-14,16-17,19,30H,2,5,10-11,15,18,20-25H2,(H,33,36) N
  • Key:NMZIDFFHGCRAJV-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

LP-12 is a drug which acts as a potent agonist at the 5HT7 serotonin receptor, with very high selectivity over other tested receptor subtypes such as the serotonin 5-HT1A and 5-HT2A, and the dopamine D2 receptor. It has been used to research the involvement of the 5-HT7 receptor in as yet poorly understood processes such as allodynia and hyperalgesia.[1]

See also

References

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