Betahydroxythiofentanyl

Betahydroxythiofentanyl

Systematic (IUPAC) name
N-{1-[2-hydroxy-2-(thiophen-2-yl)ethyl]piperidin-4-yl}-N-phenylpropanamide
Clinical data
Legal status	CA: Schedule I UK: Class A US: Schedule I
Identifiers
CAS Number	1474-34-6
ATC code	none
PubChem	CID: 62278
ChemSpider	21106268 Y
Synonyms	β-hydroxythiofentanyl
Chemical data
Formula	C20H26N2O2S
Molecular mass	358.498 g/mol
SMILES CCC(=O)N(c1ccccc1)C2CCN(CC2)CC(c3cccs3)O
InChI InChI=1S/C20H26N2O2S/c1-2-20(24)22(16-7-4-3-5-8-16)17-10-12-21(13-11-17)15-18(23)19-9-6-14-25-19/h3-9,14,17-18,23H,2,10-13,15H2,1H3 Y Key:GLAAETOTOUGGSB-UHFFFAOYSA-N Y
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β-Hydroxythiofentanyl is an opioid analgesic that is an analogue of fentanyl.

β-hydroxythiofentanyl was sold briefly on the black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. β-hydroxythiofentanyl was anecdotally said to be one of the more favored fentanyl analogues by opiate addicts, but nevertheless its brief career as a street drug did not survive the introduction of the Analogues Act.

β-hydroxythiofentanyl has similar effects to fentanyl. Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

Legal Status

As of October 2015 β-hydroxythiofentanyl is a controlled substance in China.

As of May 2016 β-hydroxythiofentanyl is a Schedule I controlled substance in the United States.