UK-414,495

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UK-414,495
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Systematic (IUPAC) name
(R)-2-({1-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]cyclopentyl}methyl)valeric acid
Identifiers
CAS Number 337962-93-3
PubChem CID: 9949799
Chemical data
Formula C16H25N3O3S
Molecular mass 339.452 g/mol
  • CCc1nnc(s1)NC(=O)C2(CC(C(O)=O)CCC)CCCC2
  (verify)

UK-414,495 is a drug developed by Pfizer for the treatment of female sexual arousal disorder.[1] UK-414,495 acts as a potent, selective inhibitor of the enzyme neutral endopeptidase, which normally serves to break down the neuropeptide VIP. The consequent increase in VIP activity alters blood flow to the genital region leading to increased lubrication and muscle relaxation.[2][3][4]

See also

References

  1. ↑ 'Female Viagra' will help women increase their sexual arousal. Daily Mail Online 14 April 2010
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found. ISSN 0214-0934
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.



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