Neurotensin receptor 2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Neurotensin receptor type 2 is a protein that in humans is encoded by the NTSR2 gene.[1][2][3]

Function

The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.[3]

See also

References

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Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.

External links

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