Bromadoline

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
Bromadoline
(1:1 mixture of trans isomers)
Bromadoline.png
Systematic (IUPAC) name
trans-4-bromo-N-(2-(dimethylamino)cyclohexyl)benzamide
Identifiers
CAS Number 67579-24-2 YesY
ATC code none
PubChem CID: 54753
ChemSpider 49457 YesY
UNII R8DWN01P1M YesY
ChEMBL CHEMBL2110893
Synonyms Bromadoline
Chemical data
Formula C15H21BrN2O
Molecular mass 325.244 g/mol
  • CN([C@H]1CCCC[C@@H]1NC(C2=CC=C(C=C2)Br)=O)C
  • InChI=1S/C15H21BrN2O/c1-18(2)14-6-4-3-5-13(14)17-15(19)11-7-9-12(16)10-8-11/h7-10,13-14H,3-6H2,1-2H3,(H,17,19)/t13-,14-/m0/s1 YesY
  • Key:UFDJFJYMMIZKLG-KBPBESRZSA-N YesY
  (verify)

Bromadoline (U-47931E)[1] is an opioid analgesic selective for the mu-opioid receptor[2] developed by the Upjohn company in the 1970s.[3] The drug has a potency lying between that of codeine and morphine being slightly stronger than pentazocine.[4] It is presumed that the (1R,2R) isomer is the active opioid, overlaying as it does with many other mu agonists.[5] Bromadoline is related to AH-7921 and U-47700.[6]

See also

References

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ U.S. Patent 4,098,904
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.


<templatestyles src="Asbox/styles.css"></templatestyles>

Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.
Retrieved from "https://infogalactic.com/w/index.php?title=Bromadoline&oldid=4866619"