Haplogroup L5 (mtDNA)

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Haplogroup L5
Possible time of origin 114,200-126,200 YBP[1]
Possible place of origin East Africa
Ancestor L2'3'4'5'6
Descendants L5a, L5c
Defining mutations 3423, 7972, 12432, 12950[2]

In human mitochondrial genetics, Haplogroup L5 is a human mitochondrial DNA (mtDNA) haplogroup. It was previously known as L1e.

Origin

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Distribution

It is a small African haplogroup from East Africa. The highest frequency is in Mbuti Pygmies at 15%.[3] It is present in relatively small frequencies in Tanzania (Sandawe and others), Kenya, Ethiopia, Sudan, Nubia, Egypt[4][Note 1] and Saudi Arabia.[5]

Subclades

Tree

This phylogenetic tree of haplogroup L5 subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.

  • Most Recent Common Ancestor (MRCA)
    • L1-6
      • L2-6
        • L5
          • L5a
            • L5a1
              • L5a1a
              • L5a1b
              • L5a1c
            • L5a2
          • L5c
            • L5c1
            • L5c2

References

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  2. 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
  3. Sarah A. Tishkoff et al. 2007, History of Click-Speaking Populations of Africa Inferred from mtDNA and Y Chromosome Genetic Variation. Molecular Biology and Evolution 2007 24(10):2180-2195
  4. Lua error in package.lua at line 80: module 'strict' not found.
  5. Abu-Amero et al. 2008 February. "Mitochondrial DNA structure in the Arabian Peninsula", BMC Evolutionary Biology. 8(45): 52.

Notes

  1. Sample UPE52 is subclade L5a.

Evolutionary tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6
L1 L2 L3   L4 L5 L6
  M   N  
CZ D E G Q   O A S   R   I W X Y
C Z B F R0   pre-JT P  U
HV JT K
H V J T

External links


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