1-(2-Diphenyl)piperazine

1-(2-Diphenyl)piperazine

Systematic (IUPAC) name
1-(2-diphenyl)piperazine
Identifiers
PubChem	CID: 2737389
ChemSpider	2019031 Y
ChEMBL	CHEMBL494675 Y
Chemical data
Formula	C16H18N2
Molecular mass	238.327 g/mol
SMILES C3CNCCN3c1ccccc1-c2ccccc2
InChI InChI=1S/C16H18N2/c1-2-6-14(7-3-1)15-8-4-5-9-16(15)18-12-10-17-11-13-18/h1-9,17H,10-13H2 Y Key:RKRVRTJVCWZOQS-UHFFFAOYSA-N Y
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1-(2-Diphenyl)piperazine, also known as RA-7, is a drug which acts as a potent and selective agonist at the 5HT₇ serotonin receptor. It was discovered as an active metabolite of the synthetic 5-HT₇ agonists LP-12 and LP-211, and unexpectedly turned out to be a similarly potent agonist with selectivity approaching that of the parent molecules, despite its much simpler structure.

See also

• Benzylpiperazine
• Naphthylpiperazine
• Phenylpiperazine