FOXJ1
Forkhead box protein J1 is a protein that in humans is encoded by the FOXJ1 gene.[1] It has been shown that this gene is a transcription factor involved in ciliogenesis.[2] Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value).
Function
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry.[1]
Clinical significance
Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[1]
References
Further reading
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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