Liver receptor homolog-1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). The liver receptor homolog-1 (LRH-1) also known as NR5A2 (nuclear receptor subfamily 5, group A, member 2) is a protein that in humans is encoded by the NR5A2 gene.[1][2] LRH-1 is a member of the nuclear receptor family of intracellular transcription factors.
LRH-1 plays a critical role in the regulation of development, cholesterol transport, bile acid homeostasis and steroidogenesis.[3][4][5]
LRH-1 is important for maintaining pluripotence of stem cells during embryonic development.[6]
Interactions
Liver receptor homolog-1 has been shown to interact with the small heterodimer partner.[7][8]
References
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Further reading
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External links
- NR5A2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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