TOX3
From Infogalactic: the planetary knowledge core
| TOX high mobility group box family member 3 | |
|---|---|
| Identifiers | |
| Symbol | TOX3 |
| Alt. symbols | TNRC9, CAGF9 |
| Entrez | 27324 |
| HUGO | 11972 |
| OMIM | 611416 |
| RefSeq | XM_049037 |
| UniProt | O15405 |
| Other data | |
| Locus | Chr. 16 q12.1 |
TOX high mobility group box family member 3, also known as TOX3, is a human gene.[1][2]
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX2, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[2]
Disease linkage
Mutations in the TOX3 gene are associated with an increased risk of breast cancer.[3][4][5][6]
References
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