TOX3
From Infogalactic: the planetary knowledge core
TOX high mobility group box family member 3 | |
---|---|
Identifiers | |
Symbol | TOX3 |
Alt. symbols | TNRC9, CAGF9 |
Entrez | 27324 |
HUGO | 11972 |
OMIM | 611416 |
RefSeq | XM_049037 |
UniProt | O15405 |
Other data | |
Locus | Chr. 16 q12.1 |
TOX high mobility group box family member 3, also known as TOX3, is a human gene.[1][2]
The protein encoded by this gene is a member of a subfamily of transcription factors that also includes TOX, TOX2, and TOX4 that share almost identical HMG-box DNA-binding domains which function to modify chromatin structure.[2]
Disease linkage
Mutations in the TOX3 gene are associated with an increased risk of breast cancer.[3][4][5][6]
References
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