ID3 (gene)
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). DNA-binding protein inhibitor ID-3 is a protein that in humans is encoded by the ID3 gene.[1][2]
Contents
Function
Members of the ID family of helix-loop-helix (HLH) proteins lack a basic DNA-binding domain and inhibit transcription through formation of nonfunctional dimers that are incapable of binding to DNA.[supplied by OMIM][2]
Interactions
ID3 (gene) has been shown to interact with TCF3.[3][4]
Repressors of ID3
BTG2 binds to the promoter of Id3 and represses its activity. By this mechanism, the upregulation of Id3 in the hippocampus caused by BTG2 ablation prevents terminal differentiation of hippocampal neurons.[5]
See also
References
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Further reading
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External links
- ID3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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